The piperazines are a broad class of chemical compounds, many with important pharmacological properties, which contain a core piperazine functional group. 103-76-4, formula is C6H14N2O, Name is N-(2-Hydroxyethyl)piperazine. A form in which piperazine is commonly available industrially is as the hexahydrate, C4H10N2. 6H2O, which melts at 44 °C and boils at 125–130 °C. Name: N-(2-Hydroxyethyl)piperazine.
Resende, Diana I. S. P.;Almeida, Joana R.;Pereira, Sandra;Campos, Alexandre;Lemos, Agostinho;Plowman, Jeffrey E.;Thomas, Ancy;Clerens, Stefan;Vasconcelos, Vitor;Pinto, Madalena;Correia-da-Silva, Marta;Sousa, Emilia research published 《 From Natural Xanthones to Synthetic C-1 Aminated 3,4-Dioxygenated Xanthones as Optimized Antifouling Agents》, the research content is summarized as follows. In this work, the antifouling activity of a series of 24 xanthones I [R1 = Me, CH2Br, 4-ClC6H4CH2NHCH2, etc.; R2 = H, Cl; R3 = OMe; R4 = OH, OMe; R5 = H, OMe], with chem. similarities to natural products, was exploited. Nine of the tested xanthones presented highly significant anti-settlement responsed against the settlement of mussel Mytilus galloprovincialis larvae and low toxicity to this macrofouling species. Addnl., xanthone I [R1 = piperidinylmethyl; R2 = H; R3 = OMe; R4 = OMe; R5 = H] exhibited a therapeutic ratio (LC50/EC50) >15, as required by the US Navy program attesting its suitability as natural antifouling agents. From the nine tested xanthones, none of the compounds were found to significantly inhibit the growth of the marine biofilm-forming bacterial strains tested. Insights on the antifouling mode of action suggested that these two compounds affected similar mol. targets and cellular processes in mussel larvae, including that related to mussel adhesion capacity. This work exposed for the first time the relevance of C-1 aminated xanthones with a 3,4-dioxygenated pattern of substitution as new non-toxic products to prevent marine biofouling.
103-76-4, 1-(2-Hydroxyethyl)piperazine is a useful research compound. Its molecular formula is C6H14N2O and its molecular weight is 130.19 g/mol. The purity is usually 95%.
1-(2-Hydroxyethyl)piperazine is a chemical solvent that is used for the absorption of amines and other compounds. It has been shown to have a high affinity for acidic substances, which may be due to its ability to form hydrogen bonds with them. 1-(2-Hydroxyethyl)piperazine is also used in sample preparation for the analysis of amines and other compounds in fruit extracts. The solubility of 1-(2-Hydroxyethyl)piperazine depends on the experimental conditions, including pH, temperature, and pressure. FT-IR spectroscopy has been used to measure the vibrational modes of 1-(2-Hydroxyethyl)piperazine molecules. The IR spectrum revealed that this compound contains a hydroxyl group and two fatty acid chains with one or more hydroxyl groups at their terminal end. The nmr spectrum showed that 1-(2-Hydroxyethyl)piperazine contains an NH proton as well as, Name: N-(2-Hydroxyethyl)piperazine
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics