Piperazine is an organic compound that consists of a six-membered ring containing two nitrogen atoms at opposite positions in the ring. 103-76-4, formula is C6H14N2O, Name is N-(2-Hydroxyethyl)piperazine. Piperazine exists as small alkaline deliquescent crystals with a saline taste. Application of C6H14N2O.
Al-Qawasmeh, Raed A.;Hussein, Nura A.;Shehadi, Ihsan;Khanfar, Monther A.;Salameh, Bader A. research published 《 Design and Synthesis of Aminoacetylenic Indole and Carbazole Hybrid Compounds》, the research content is summarized as follows. A novel series of aminoacetylenic indole and carbazole hybrid compounds I [R = (4-ethylpiperazin-1-yl)methyl, [4-(pyrimidin-2-yl)piperazin-1-yl]methyl, morpholin-4-ylmethyl, thiomorpholin-4-ylmethyl, piperidin-1-ylmethyl, etc.; R1 = H; R2 = H, C(O)OCH2CH3, C(O)OH; R1R2 = -CH=CHCH=CH-]had been prepared via a three-component reaction system in which a Mannich type reaction was used in the coupling of propargylic indoles or carbazole I (R = H) with cyclic amines II [X = N, O, S, CH2; R3 = Et, pyridin-2-yl, pyrimidin-2-yl, 4-(1H-indol-1-yl)but-2-yn-1-yl, etc.] and formaldehyde in the presence of Cu(I) catalyst. A side product of the self-coupling reaction of propargylic indole was also separated and characterized by physicochem. techniques. NMR, single crystal x-ray, and High-resolution mass spectra (HRMS) are used in the characterization of the synthesized compounds and intermediates.
Application of C6H14N2O, 1-(2-Hydroxyethyl)piperazine is a useful research compound. Its molecular formula is C6H14N2O and its molecular weight is 130.19 g/mol. The purity is usually 95%.
1-(2-Hydroxyethyl)piperazine is a chemical solvent that is used for the absorption of amines and other compounds. It has been shown to have a high affinity for acidic substances, which may be due to its ability to form hydrogen bonds with them. 1-(2-Hydroxyethyl)piperazine is also used in sample preparation for the analysis of amines and other compounds in fruit extracts. The solubility of 1-(2-Hydroxyethyl)piperazine depends on the experimental conditions, including pH, temperature, and pressure. FT-IR spectroscopy has been used to measure the vibrational modes of 1-(2-Hydroxyethyl)piperazine molecules. The IR spectrum revealed that this compound contains a hydroxyl group and two fatty acid chains with one or more hydroxyl groups at their terminal end. The nmr spectrum showed that 1-(2-Hydroxyethyl)piperazine contains an NH proton as well as, 103-76-4.
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics