The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 1,10-Phenanthroline(SMILESS: C1=CC3=C(C2=NC=CC=C12)N=CC=C3,cas:66-71-7) is researched.HPLC of Formula: 54903-09-2. The article 《Synthesis and photophysical properties of metal complexes of curcumin dyes: Solvatochromism, acidochromism, and photoactivity》 in relation to this compound, is published in Dyes and Pigments. Let’s take a look at the latest research on this compound (cas:66-71-7).
Curcumin and its dyes have attracted attention due to their environment-sensitivity and optical properties. However, the free mol. has low photoactivity, which is a limitation for use in photodynamic therapy. To overcome this limitation, we proposed the chelation of a D-π-A-π-D curcumin dye (1) with the metals Cu (II) and Pd (II). The photophys. properties of the curcumin dyes were investigated in different solvents, using UV-vis spectroscopy and time-resolved/steady-state fluorescence techniques. In our results, all curcumin dyes exhibited a pos. solvatochromism from non-polar to polar solvents, with the Stokes’ shift in the range of 1895-4970 cm-1. The acidochromism studies were performed in chloroform solution and TLC plates using trifluoroacetic acid (TFA). The results exhibited a neg. acidochromism and fluorescence quenching upon gradual addition of TFA, demonstrating reversibility upon addition of triethylamine (TEA). The main mechanism which influences the solvatochromism/acidochromism is the ICT system and fluorescence lifetime decays exhibited mono-exponential fit for aprotic solvents and bi-exponential fit for protic solvents (EtOH and MeOH). Compared to the curcumin ligand (1), the metal complexes (1a-b) exhibited higher singlet oxygen quantum yields (ΦΔ = 0.36 and 0.54, resp.). The in vitro antimicrobial photoactivity of the compounds was evaluated against six different microorganisms. The results showed that the metal complexes (1a-b) exhibited both antileishmanial (MIC = 2.29μM against Leishmania amazonensis promastigotes) and antifungal (IC50 = 10μM against Sporothrix brasiliensis yeasts) activities, while the ligand showed no activity, suggesting the chelation with the metals Cu (II) and Pd (II) may improve its photoactivity.
In addition to the literature in the link below, there is a lot of literature about this compound(1,10-Phenanthroline)SDS of cas: 66-71-7, illustrating the importance and wide applicability of this compound(66-71-7).
Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics