Aichaoui, Hocine; Poupaert, Jacques H.; Lesieur, Daniel; Henichart, Jean Pierre published the article 《Regioselectivity in the C-acylation of 2(3H)-benzoxazolones》. Keywords: benzoxazolone acylation regioselectivity; acylbenzoxazolone preparation NMR; acylaminophenol cyclocondensation urea.They researched the compound: 6-Acetylbenzo[d]oxazol-2(3H)-one( cas:54903-09-2 ).HPLC of Formula: 54903-09-2. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:54903-09-2) here.
C-acylation of benzoxazolone I (R = R1 = H) using either carboxylic acids R2CO2H and polyphosphoric acid as solvent and catalyst or under Friedel-Crafts conditions using acid halides or anhydrides in presence of AlCl3 in DMF gave only 6-acylbenzoxazolones I (R = H, R1 = COR2, R2 = Me, Et, CHBrMe, Ph, 2-thienyl). This observation contradicts previously published results. 5-Acylbenzoxazolones I (R = COR2, R2 as above, R1 = H) were prepared by the cyclocondensation of 4-acyl-2-aminophenols II (R2 as above) with urea. Proton NMR of 5- and 6-acylbenzoxazolones are reported.
In addition to the literature in the link below, there is a lot of literature about this compound(6-Acetylbenzo[d]oxazol-2(3H)-one)HPLC of Formula: 54903-09-2, illustrating the importance and wide applicability of this compound(54903-09-2).
Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics