The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: (S)-1-(Dimethylamino)propan-2-ol( cas:53636-17-2 ) is researched.COA of Formula: C5H13NO.Gennari, Cesare; Molinari, Francesco; Cozzi, PierGiorgio; Oliva, Ambrogio published the article 《Auxiliary structure and asymmetric induction in the Mukaiyama-aldol reactions of chiral silyl ketene acetals》 about this compound( cas:53636-17-2 ) in Tetrahedron Letters. Keywords: auxiliary structure asym induction Mukaiyama aldol; silyl ketene acetal asym condensation aldehyde. Let’s learn more about this compound (cas:53636-17-2).
A variety of chiral auxiliaries [e.g., (1S,2R-Me2NCHMeCHPhOH, (S)-Me2NCH2CHMeOH] were prepared and tested for levels of asym. induction control in the Mukaiyama-aldol reaction of chiral silyl ketene acetals. Structural features required for high levels of control are discussed.
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Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics