The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 2-Bromopriopionaldehydediethylacetal, is researched, Molecular C7H15BrO2, CAS is 3400-55-3, about A Flexible Strategy for the Regiocontrolled Synthesis of Pyrazolo[1,5-a]pyrazines, the main research direction is pyrazolopyrazine preparation; pyrazole alkylation formylation cyclization reductive amination.Safety of 2-Bromopriopionaldehydediethylacetal.
A four-step protocol for the synthesis of pyrazolo[1,5-a]pyrazines was developed. Com. available pyrazoles were alkylated and formylated in a regiocontrolled manner to give pyrazole-5-aldehydes bearing 2,2-dialkoxyethyl substitution on N-1. Efficient conditions for the subsequent deprotection and cyclization of these intermediates allowed access to pyrazolo[1,5-a]pyrazines with multiple substitution patterns. The versatility of the pyrazole-5-aldehyde intermediates was further demonstrated through a deprotection and double-reductive amination sequence to give 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazines.
As far as I know, this compound(3400-55-3)Safety of 2-Bromopriopionaldehydediethylacetal can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.
Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics