Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 2-Bromopriopionaldehydediethylacetal, is researched, Molecular C7H15BrO2, CAS is 3400-55-3, about Alkylation of disodiopentane-2,4-dione with halo acetals.Recommanded Product: 2-Bromopriopionaldehydediethylacetal.
NaCH2COCHNaCOMe with RCH2CH(OR1)2 (I; R = Br, R1 = Me, Et, CH2) gave 49, 46, and 38% (R1O)2CH(CH2)2COCH2COMe, resp. Similarly Br(CH2)2CH(OEt)2 and Cl(CH2)2CH(OCH2)2 gave dioxooctanal acetals. The lack of reactivity between I (R = Cl, R1 = Me, Et, CH2) and NaCH2COCHNaCOMe was explained by steric hindrance and the leaving group ability of Cl.
There is still a lot of research devoted to this compound(SMILES:CC(Br)C(OCC)OCC)Recommanded Product: 2-Bromopriopionaldehydediethylacetal, and with the development of science, more effects of this compound(3400-55-3) can be discovered.
Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics