Safety of 6-Acetylbenzo[d]oxazol-2(3H)-one. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 6-Acetylbenzo[d]oxazol-2(3H)-one, is researched, Molecular C9H7NO3, CAS is 54903-09-2, about Acylation of 2,3-dihydrobenzoxazol-2-one in a two-step method involving an acyl migration. Author is Cotelle, Nicole; Cotelle, Philippe; Lesieur, Daniel.
Acylation of dihydrobenzoxazolone I (R = R1 = H) with (R2CO)2O or with R2COCl in pyridine gave 90-99% I (R = R2 = Me, Pr, Me2CHCH2, Ph, o-, p-ClC6H4, etc.; R1 = H) (II). Treatment of II with polyphosphoric acid caused acyl migration to give 80-99% I (R = H, R1 = R2).
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