Awesome Chemistry Experiments For 54903-09-2

If you want to learn more about this compound(6-Acetylbenzo[d]oxazol-2(3H)-one)Name: 6-Acetylbenzo[d]oxazol-2(3H)-one, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(54903-09-2).

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Synthesis of some new substituted Di-tert-butylphenols as potential COX-2 inhibitors, published in 2004-09-30, which mentions a compound: 54903-09-2, mainly applied to aryl ketone benzaldehyde condensation; benzoxazolyl aryl propenone preparation; benzoxazinyl aryl propenone preparation, Name: 6-Acetylbenzo[d]oxazol-2(3H)-one.

Selective cyclooxygenase-2 (COX-2) inhibitors have been shown to be potent antiinflammatory agents with fewer side effects than currently marketed nonsteroidal antiinflammatory drugs (NSAIDs). In previous researches, di-tert-butylphenol derivatives were more potent and selective for COX-2 vs. COX-1 based on enzyme assays, the synthesis of benzoxazole-, benzoxazolinone- and benzoxazinone- derived di-tert-butylphenols in order to increase potential COX-2 inhibitory activity is described. Starting from the readily available 6-acetyl-2-benzoxazolinone, some substituted di-tert-butylphenols were prepared in good yield.

If you want to learn more about this compound(6-Acetylbenzo[d]oxazol-2(3H)-one)Name: 6-Acetylbenzo[d]oxazol-2(3H)-one, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(54903-09-2).

Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics