Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: (S)-Methyl 3-hydroxybutanoate, is researched, Molecular C5H10O3, CAS is 53562-86-0, about Practical asymmetric hydrogenation of β-keto esters at atmospheric pressure using chiral Ru(II) catalysts.HPLC of Formula: 53562-86-0.
New practical conditions of asym. hydrogenation of β-keto esters with chiral Ru(II) catalysts are described. It is now possible to carry out the reaction at atm. pressure. Under these conditions, β-keto esters are hydrogenated to β-hydroxy esters with excellent enantiomeric excesses (up to 99%) using chiral ruthenium (II) catalysts easily prepared in situ by treatment of com. available (COD)Ru(2-methylallyl)2 in the presence of the appropriate chiral ligands such as Binap, MeO-Biphep and Me-Duphos.
Here is a brief introduction to this compound(53562-86-0)HPLC of Formula: 53562-86-0, if you want to know about other compounds related to this compound(53562-86-0), you can read my other articles.
Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics