192330-11-3, (R)-1-Boc-Piperazine-3-carboxylic acid is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
EXAMPLE 110(“i?V4-r2-(2-Fluoro-4-iodophenylaminoV5,5-dimethyl-8-oxo-5,6.7.8-tetrahvdro-4H- thieno[2,3-c]azepin-3-ylcarbonyl1piperaziiie-l,3-dicarboxylic acid; 1-fert-butyl ester triethylamine salt(i?)-4-N-tert-Butoxycarbonylpiperazine-2-carboxylic acid (346 mg, 1.50 mmol) was added to a solution of Intermediate 5 (300 mg, 0.46 mmol) and triethylamine (0.33 mL, 2.3 mmol) in DCM (8 mL). The mixture was stirred at room temperature for 18 h. Water (75 mL) was added and the mixture extracted with DCM (3 x 100 mL). The combined organic extracts were washed with brine (100 mL), dried (MgSO4), filtered and concentrated in vacuo. The crude product was purified by chromatography (silica, 0-10% methanol in DCM) to give the title compound as a white solid (266 mg, 74%). LCMS (ES+) RT 2.72 minutes, 687.1 (M+H)+., 192330-11-3
The synthetic route of 192330-11-3 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; UCB PHARMA S.A.; WO2008/20206; (2008); A2;,
Piperazine – Wikipedia
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