Sep 2021 News Analyzing the synthesis route of Piperazin-2-one

As the paragraph descriping shows that 5625-67-2 is playing an increasingly important role.

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.5625-67-2,Piperazin-2-one,as a common compound, the synthetic route is as follows.

5625-67-2, Piperazine-2-one (1.0 g, 10 mmol) was suspended in 10 mL DCM and Boc2O was slowly added.After the addition was completed, the reaction was allowed to stand at room temperature overnight.After completion of the reaction, it was washed three times with 0.1 N diluted hydrochloric acid, 20 ml each time, and washed three times with saturated potassium carbonate, 20 ml each time.Finally, anhydrous sodium sulfate was added and the solution was removed in vacuo to give a white solid.

As the paragraph descriping shows that 5625-67-2 is playing an increasingly important role.

Reference:
Patent; Shaoxing University; Hu Chunqi; Li Xin; Shi Yaru; Du Wenting; Tong Jie; Su Wanting; Xia Weiqi; (21 pag.)CN108610333; (2018); A;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics