109-01-3, 1-Methylpiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
a) Synthesis of 1-(4-methylpiperazin-1-yl)ethanone A solution of N-methylpiperazine (2.0 g, 19.97 mmol), triethylamine (3.35 mL, 23.96 mmol) and acetic anhydride (2.3 mL, 23.96 mmol) in EtOH (60 mL) was stirred at room temperature overnight. The reaction mixture was evaporated to dryness. Purification of the residue by silica gel column chromatography (CH2Cl2: MeOH mixtures of increasing polarity as eluent) afforded the desired product (2.16 g, 76%) as a yellow oil. 1H-NMR (CDCl3, 300 MHz) delta: 3.65 (t, J= 6.8 Hz, 2H), 3.49 (t, J= 6.8 Hz, 2H), 2.46-2.39 (m, 4H), 2.32 (s, 3H), 2.10 (s, 3H) ppm., 109-01-3
As the paragraph descriping shows that 109-01-3 is playing an increasingly important role.
Reference:
Patent; Laboratorios del. Dr. Esteve, S.A.; Alcalde-Pais, Maria de las Ermitas; Almansa-Rosales, Carmen; Diaz-Fernandez, Jose-Luis; Mesquida-Estevez, Maria de les Neus; Paloma-Romeu, Laura; EP2682391; (2014); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics