4318-42-7, 1-Isopropylpiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: A mixture of 2-(5-iodomethyl-2-oxo-oxazolidin-3-yl)-N-(6-methoxy-2-methyl-quinolin-4-yl)-acetamide (12, 0.2 g, 0.439 mmol), potassium carbonate (0.151 g, 1.09 mmol), different substituted amines (1.1 mmol) in 10 mL of acetonitrile was heated to 80 °C for 4 h. The reaction completion was monitored by TLC and when the reaction was completed, the reaction mass was filtered through a celite bed, filtrate was concentrated under reduced pressure. The crude residue was purified using biotage parallel column purifier using ethyl acetate in petroleum ether (4:1) to 4-6percent methanol in dichloromethane as eluant. The spectral data for the final compounds, 13a-n is given below.
4318-42-7, 4318-42-7 1-Isopropylpiperazine 78013, apiperazines compound, is more and more widely used in various fields.
Reference：
Article; Thomas; Adhikari, Airody Vasudeva; Chowdhury, Imran H.; Sandeep; Mahmood; Bhattacharya; Sumesh; European Journal of Medicinal Chemistry; vol. 46; 10; (2011); p. 4834 – 4845;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics