115619-01-7, 4-(4-Ethylpiperazin-1-yl)phenylamine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Example 59; 6-Acetyl-8-ethyl-2-[4-(4-ethylpiperazin-l-yl)phenylamino]-4-methylpyrido[2,3-c(jpyrimidin-7(8H)-one; [00246] A mixture of 6-bromo-8-ethyl-4-methyl-2-(methylsulfonyl)-6- phenylpyrido[2,3-J]pyrimidin-7(8H)-one from above (502 mg, 1.46 mmol) and 4-(4- ethylpiperazin-l-yl)aniline (3.45 g, 16.8 mmol) were heated (the neat mixture melted upon heating) at 170 C for ten minutes and cooled to room temperature. The reaction was partitioned between aqueous and organic layers with ethyl acetate and H2O. The organic layer was dried with anhydrous magnesium sulfate, filtered and evaporated, and directly applied to prep-LC to provide product (320 mg, 46.5 % yield); 471.0 [M+H]., 115619-01-7
115619-01-7 4-(4-Ethylpiperazin-1-yl)phenylamine 936738, apiperazines compound, is more and more widely used in various fields.
Reference：
Patent; EXELIXIS, INC.; WO2007/44698; (2007); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics