With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.115619-01-7,4-(4-Ethylpiperazin-1-yl)phenylamine,as a common compound, the synthetic route is as follows.
General procedure: A solution of compound 4 or 5 (1 mmol) and the appropriate aniline (1 mmol) in n-butanol (5 mL) was stirred at 100 C for 5 h. The reaction mixture was then cooled to room temperature, evaporated under reduced pressure, and the residue was purified either by flash column chromatography or precipitation., 115619-01-7
As the paragraph descriping shows that 115619-01-7 is playing an increasingly important role.
Reference：
Article; Elkamhawy, Ahmed; Al-Sanea, Mohammad M.; Song, Chiman; Sim, Taebo; Roh, Eun Joo; Bulletin of the Korean Chemical Society; vol. 36; 7; (2015); p. 1863 – 1873;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics