122833-04-9, 2-Methoxy-4-(4-methylpiperazin-1-yl)aniline is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
/?-Toluenesulfonic acid monohydrate (0.304 g) was added to a mixture of 2-chloro-7-methyl-9-piperidin-4-yl-7,9-dihydro-8H-purin-8-one 4-methylbenzene- sulfonate (Method 38, 0.176 g), and 2-methoxy-4-(4-methylpiperazin-l-yl)aniline (Compound 46-3, page 138 in WO 04/080980, 0.089 g) in 4-methyl-2-pentanol (3 mL). The resulting suspension was heated at 16O0C for Ih in a microwave. The cooled solution was decanted and the residue was purified by RPetaPLC to provide the title compound as a brown gum (0.142 g, 57 %); 1H NMR: 1.94 (2H, m), 2.29 (6H, s), 2.60 (obscured, m), 3.12 (6H, m), 3.35 (obscured, m), 3.85 (3H, s), 4.52 (IH, m), 6.52 (IH, m), 6.66 (IH, d), 7.12 (2H, d), 7.40 (IH, s), 7.48 (2H, d), 8.06 (IH, d), 8.11 (IH, s); m/z: MH+ 453; EAA2: 5.36.
122833-04-9, 122833-04-9 2-Methoxy-4-(4-methylpiperazin-1-yl)aniline 20136253, apiperazines compound, is more and more widely used in various fields.
Reference:
Patent; ASTRAZENECA AB; ASTRAZENECA UK LIMITED; WO2009/24824; (2009); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics