Analyzing the synthesis route of 169447-70-5

169447-70-5, As the paragraph descriping shows that 169447-70-5 is playing an increasingly important role.

169447-70-5, (S)-tert-Butyl 2-methylpiperazine-1-carboxylate is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To a solution of 5-fluoro-2-methyl-3-nitrobenzaldehyde (D32, 10 g) and (S)-tert-butyl 2-methylpiperazine-1 -carboxylate (12.03 g) in DCM (120 mL) was added drops of acetic acid (3.28g). The mixture was stirred at RT for an hour. Sodium triacetoxyhydroborate (23.15 g) was added in ice-bath. The mixture was stirred at RT overnight and quenched with sat. NaHCO3 solution. The organic layer was dried with anhydrous Na2SO4, filtered and concentrated in vacuo to afford the title compound (22.17 g). MS (ESI): C18H26FN304 requires 367; found 368 [M+H].

169447-70-5, As the paragraph descriping shows that 169447-70-5 is playing an increasingly important role.

Reference:
Patent; GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED; GLAXOSMITHKLINE (CHINA) R & D COMPANY LIMITED; DENG, Jing; LEI, Hui; MA, Xin; REN, Feng; CAI, Wei; LIN, Xichen; WO2015/180613; (2015); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics