4318-42-7,With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.4318-42-7,1-Isopropylpiperazine,as a common compound, the synthetic route is as follows.
General procedure: A mixture of 2-chloro-N-(5-methyl/ethyl-1,3,4-thiadiazol-2-yl)acetamide (1a or 1b) (2.6 mmol), appropriate piperazine derivatives (2.6 mmol) and potassium carbonate (2.6 mmol, 0.363 g) as acatalytic agent were stirred in acetone (100 mL) for 5 h at 25 °C. The mixture was filtered to remove potassium carbonate and acetone was evaporated. The residue was recrystallized from EtOH.
4318-42-7 1-Isopropylpiperazine 78013, apiperazines compound, is more and more widely used in various fields.
Reference：
Article; Can, Nafiz nc; Can, zg r Devrim; Osmaniye, Derya; Zkay, mide Demir; Molecules; vol. 23; 4; (2018);,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics