960283-58-3, (S)-tert-Butyl 2-methylpiperazine-1-carboxylate hydrochloride is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Description 1; 1 ,1 -Dimethylethyl (2S)-2-methyl-4-[(4-nitrophenyl)methyl]-1 – piperazinecarboxylate (D1); A mixture of 4-nitrobenzaldehyde (15.1g, O.imol), 1 ,1-dimethylethyl (2S)-2-methyl-1- piperazinecarboxylate hydrochloride (21.3g, 0.09mol), triethylamine (15mL, 0.108mol) and sodium tri(acetoxy)borohydride (42.4g, 0.2mol) in 1 ,2-DCE (50OmL) was stirred at room temperature overnight. Saturated aqueous NaHCO3 solution (20OmL) was added and the mixture stirred for 20-30 minutes. The phases were separated and the aqueous phase was washed with DCM. The combined organics were washed with brine, dried and concentrated. Column chromatography eluting with 0-20% EtOAc/hexane gave the title compound as a pale yellow oil which crystallized on standing (25.61 g). deltaH (CDCI3, 400MHz) 8.19 (2H1 d), 7.53 (2H, d), 4.21 (1 H, br.s), 3.83 (1 H, d), 3.62 (1 H, d), 3.50 (1H, d), 3.13 (1 H, td), 2.74 (1 H, m), 2.54 (1 H, m), 2.20 (1 H, dd), 2.08 (1 H, m), 1.46 (9H, s), 1.25 (3H, d)., 960283-58-3
960283-58-3 (S)-tert-Butyl 2-methylpiperazine-1-carboxylate hydrochloride 45072182, apiperazines compound, is more and more widely used in various fields.
Reference：
Patent; GLAXO GROUP LIMITED; WO2008/729; (2008); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics