31166-44-6, 1-Cbz-Piperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: To a solution of compound 7 (0.16 g, 0.37 mmol) and isonipecotic acid ethyl ester (0.086 ml, 0.56 mmol) in CH2Cl2 was added WSCI*HCl (0.11 g) and HOBt (0.085 g), and then the mixture was stirred at room temperature for 18 h. The reaction mixture was diluted with water and the organics were extracted with CH2Cl2. The extract was washed with brine, dried over Na2SO4, then concentrated in vacuo, and then the residue was purified with silica gel column chromatography (0-5percent MeOH-CH2Cl2 as eluent) to give compound 8 (0.16 g, 0.28 mmol, 76percent) as a colorless powder., 31166-44-6
The synthetic route of 31166-44-6 has been constantly updated, and we look forward to future research findings.
Reference：
Article; Ichikawa, Masanori; Yokomizo, Aki; Itoh, Masao; Sugita, Kazuyuki; Usui, Hiroyuki; Shimizu, Hironari; Suzuki, Makoto; Terayama, Koji; Kanda, Akira; Bioorganic and Medicinal Chemistry; vol. 19; 6; (2011); p. 1930 – 1949;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics