With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.197638-83-8,1-Boc-4-(4-Formylphenyl)piperazine,as a common compound, the synthetic route is as follows.
Example 24 te/t-Butyl 4-(4-(6-bromo-7-(4-(4-chlorobenzyl)piperazin-1-yl)-3H-imidazo[4,5- C6H4CI), 7.41 (m, 4H, C6H4CI), 7.07 (d, J = 8.9 Hz1 2H) and 8.04 (d, J = 8.9 Hz, 2H)(2,6-C6H4 and 3,5-C6H4), 8.17 (s, 1H, imidazo[4,5-/b]pyridine 5-H), 13.23 (br s, 1H, imidazo[4,5-b]pyridine N-H);LC (Method B) – MS (ESI, m/z): Rt = 4.55 min – 666, 668, 670 [(M+H)+, BrCI isotopic pattern]., 197638-83-8
The synthetic route of 197638-83-8 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; CHROMA THERAPEUTICS LTD.; WO2009/1021; (2008); A1;,
Piperazine – Wikipedia
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