76003-29-7, 1-Boc-3-Oxopiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
76003-29-7, To a solution of 50.0 mmol of 5 and 60.0 mmol of 7 in 50.0 mL of 1,4-dioxane was added 0.500 mmol of copper (I) iodide followed by the addition of 100 mmol of K3PO4 and 5 mmol of trans-cyclohexanediamine, then the resulting mixture was stirred at 100 C. for 16 h. The reaction mixture was cooled to rt and diluted with 500 mL of H2O. The resulting aqueous solution was extracted with CHCl3. The organic phase was washed with saturated NaCl, dried over MgSO4 and concentrated in vacuo. The crude product was purified by column chromatography to give 43.4 mmol of 8. 4.2.a tert-Butyl 4-(6-aminopyridin-3-yl)-3-oxopiperazine-1-carboxylate 1H NMR (400 MHz, CDCl3) delta 7.97-8.00 (m, 1H), 7.35-7.40 (m, 1H), 6.50-6.54 (m, 1H), 4.54 (br s, 2H), 4.24 (s, 2H), 3.65-3.69 (m, 2H), 3.75-3.80 (m, 2H), 1.50 (s, 9H); MS m/z: 293 (M+1).
76003-29-7 1-Boc-3-Oxopiperazine 3157178, apiperazines compound, is more and more widely used in various fields.
Reference：
Patent; ICAgen, Inc.; Astellas Pharma Inc.; US2005/239800; (2005); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics