With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.17766-28-8,1-Cyclohexylpiperazine,as a common compound, the synthetic route is as follows.
Dissolving Intermediate 5 in DMSO, then adding triethylamine and 1-cyclohexyl piperazine into the solution at temperature about 50-70 C. Adding MTBE and MeOH solution. Isolation and washing of the wet cake with MTBE and MeOH followed by filtering provided Intermediate 6 as a solid
17766-28-8, The synthetic route of 17766-28-8 has been constantly updated, and we look forward to future research findings.
Reference：
Patent; VM Oncology LLC; Wu, Jay Jie-Qiang; US2015/218132; (2015); A1;,
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