30459-17-7, 1-(4-Trifluoromethylphenyl)piperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,30459-17-7
Dark brown solid; IR (KBr, cm-1): v 3282 (-NH), 3068-3076 (-CH str.), 2223 (CN), 1256 (C-O-C), 833 (s-triazine C-N str.), 749 (C-F). 1H NMR (400 MHz, Me2SO-d6): delta 9.18 (s, 1H, -NH, s-triazine to amino-benzonitrile linkage), 8.10 (d, J = 7.4 Hz, 1H, C8 proton of quinoline), 7.77 (t, J = 7.6 Hz, 1H, C7 proton of quinoline), 7.59 (d, J = 8.6 Hz, 1H, C5 proton of quinoline), 7.52 (t, J = 7.2 Hz, 1H, C6 proton of quinoline), 7.39 (s, 1H, C3 proton of quinoline), 7.26-6.93 (7H, m, Ar-H), 3.89 (4H, br s, piperazine), 3.77 (s, 3H, N-CH3), 3.51 (4H, br s, piperazine). 13C NMR (100 MHz, Me2SO-d6): delta 175.8 (1C, C-6, s-triazine, C-N at piperazine linkage), 167.5 (1C, C-4, s-triazine, C-O-C at quinoline linkage), 165.5, 163.6 (2C, 1C at C-2, s-triazine, C-NH at benzonitrile moiety and 1C of CO), 144.8-116.7 (22C, Ar. C including 2C-CF3 at 129.9, 130.4 and 2CF3 at 125.2, 125.7), 105.9 (1C, CN), 95.8 (1C, -C-CN), 48.2, 45.6 (4C, piperazine ring carbon atoms), 30.6 (1C, N-CH3). 19F NMR (400 MHz, CDCl3): delta -66.03, -63.29 (6F, s, -CF3 of piperazine moiety and -CF3 of amino benzonitrile moiety).
30459-17-7 1-(4-Trifluoromethylphenyl)piperazine 121718, apiperazines compound, is more and more widely used in various fields.
Reference：
Article; Patel, Rahul V.; Kumari, Premlata; Rajani, Dhanji. P.; Chikhalia, Kishor H.; Journal of Fluorine Chemistry; vol. 132; 9; (2011); p. 617 – 627;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics