Simple exploration of 4-((4-Methylpiperazin-1-yl)methyl)benzoic acid

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106261-48-7, 4-((4-Methylpiperazin-1-yl)methyl)benzoic acid is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

[00130] To a solution of 5-(3-amino-phenylamino)-l,3-dihydro-indol-2-one (20 mg, 0.083 mmol) in DMF (2ml) is added 4-(4-methyl-piperazin-l-ylmethyl)-benzoic acid (31 mg, 0.1 mmol), N,N-diisopropylethylamin (54 mg, 0.42 mmol), EDCI (32 mg, 0.17 mmol) and HOBt (11 mg, 0.083 mmol). The reaction is stirred for 12 hours and EPO concentrated. The residue is purified by HPLC to afford the desired compound: LC-MS: 456.2 (MH+).

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Reference：
Patent; IRM LLC; WO2006/52936; (2006); A2;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics