115619-01-7, 4-(4-Ethylpiperazin-1-yl)phenylamine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Example No. 125Preparation of N- (4- (4-ethylpiperazin-l-yl) phenyl) -5-(imidazo [1, 2-a] pyridin-2-yl) -lH-pyrazolo [4, 3-d] pyrimidin-7- amine7-chloro-5- (imidazo [1, 2-a] pyridin-2-yl) -2- (4 -methoxybenzyl) – 2H-pyrazolo [4 , 3-d] pyrimidine (0.16 mmol) and 4- (4- ethylpiperazin-l-yl) aniline (0.3 mmol 2 eq.,) were suspended in MeOH (dry, 3mL) in a microwave vial (2-5mL) , HC1 in dioxane (4M, 3 drops) was added. The reaction mixture was irradiated in a microwave reactor for 5 min at 140C. The reaction mixture was evaporated and used without further purification. The residue was dissolved in TFA (3mL) . The reaction mixture was irradiated in a microwave reactor for 5 min at 1 0C. The reaction mixture was concentrated and purified by semi- preparative HPLC-MS and freeze dried from water/t-BuOH 4/1. exact mass: 439.2607 g/mol HPLC-MS: analytical method Crt: 1.787 min – found mass: 440 (m/z+H)
115619-01-7, The synthetic route of 115619-01-7 has been constantly updated, and we look forward to future research findings.
Reference：
Patent; ORIGENIS GMBH; ALMSTETTER, Michael; THORMANN, Michael; TREML, Andreas; TRAUBE, Nadine; WO2012/143144; (2012); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics