115619-01-7, 4-(4-Ethylpiperazin-1-yl)phenylamine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: 1 equiv of piperazinyl amine was dissolved in pyridine (20 ml/g)and stirred at 0 C under inert atmosphere. 1.2 equiv of cinnamoylchloride derivative was dissolved in dry DCM (10 ml/g) and addeddropwise to above stirred solution at 0 C. The reaction mixturewasstirred for 3 h and was monitored by TLC. After completion of thereaction, the reaction mixturewas diluted withwater (20 ml/g) andethyl acetate (30 ml/g) followed by 2 N HCl to make it acidic. Theprecipitate came out which was filtered as yellow solid and furtherwashed with 2 N HCl and then water. The precipitate was suspendedin saturated bicarbonate solution and stirred vigorously toremove acid impurities. The crude compound was purified eitherby column chromatography or by recrystallization from ethyl acetateand hexane., 115619-01-7
As the paragraph descriping shows that 115619-01-7 is playing an increasingly important role.
Reference：
Article; Patel, Kavitkumar N.; Telvekar, Vikas N.; European Journal of Medicinal Chemistry; vol. 75; (2014); p. 43 – 56;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics