13889-98-0, 1-Acetylpiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: In a 25 mL two-necked round bottomed flask benzoxazole (1.0 mmol), AcOH (2.0 mmol), amine (2.0 mmol), and NIS (0.05 mmol) were added. The cold aqueous solution of H2O2 (2.0 mmol) was slowly added to the above suspension followed by 5 mL acetonitrile. Then the above mixture was kept under stirring condition till the completion of reaction. The progress of the reaction was monitored using gas chromatography. After completion of reaction the reaction mixture was extracted with ethyl acetate and treated with saturated solution of Na2CO3. Then consecutive water washing was given to the organic layer. The organic layer was separated, dried over anhydrous sodium sulphate followed by removal of solvent under reduced pressure. The reaction mixture was analyzed using a gas chromatography (Perkin Elmer, Clarus 400) equipped with a flame ionization detector (FID) and capillary column. The crude product was purified by column chromatography (silica gel, 100-200 mesh; petroleum ether/ethyl acetate, 90:10) to afford pure products. All the prepared compounds were confirmed by comparing with their authentic samples and were characterized by GC-MS (Shimadzu QP 2010), 1H NMR (Varian 500 MHz).
13889-98-0, The synthetic route of 13889-98-0 has been constantly updated, and we look forward to future research findings.
Reference：
Article; Wagh, Yogesh S.; Sawant, Dinesh N.; Bhanage, Bhalchandra M.; Tetrahedron Letters; vol. 53; 27; (2012); p. 3482 – 3485;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics