5271-27-2, 1-Methyl-3-phenylpiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
1 -Methyl-3-phenylpiperazine (17.6 g; 0.1 mol) was dissolved in 100 dichloromethane. Triethylamine (15 ml; 0.1 mol) was added. A solution of benzoyl chloride (16 g; 0.1 14 mol) in dichloromethane was slowly added under cooling. After the total addition a white suspension was formed. The mixture was quenched with 10percent sodium carbonate. The organic layer was washed again with carbonate, dried and evaporated to an oil (ca 30 g). Purification by silica filtration using CH2CI2/Me0H (95:5). Evaporation of the appropriate fractions yielded 26.2 g oil (94 percent) Chiral GC: no separation using various methods.
5271-27-2, 5271-27-2 1-Methyl-3-phenylpiperazine 2760009, apiperazines compound, is more and more widely used in various fields.
Reference：
Patent; N.V. ORGANON; WO2007/144409; (2007); A1;,
Piperazine – Wikipedia
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