128019-59-0, 4-(tert-Butoxycarbonyl)piperazine-2-carboxylic acid is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Example 10; Piperazine-1, 2,4-tricarboxylic acid 4-tert-butyl ester 1- (9H-fluoren-9-ylmethyl) ester; A solution of 9-fluorenylmethyl chloroformate (2.72 g, 10.5 mmol) in 1,4-dioxane (19 mL) was added drop-wise to a solution of piperazine-1, 3-dicarboxylic acid 1-tert-butyl ester (2.20 g, 9.6 mmol) and N, N-diisopropylethylamine (4.2 mL, 23.9 mmol) in water (9.5 mL) in an ice-bath. After stirring overnight at room temperature, the reaction mixture was diluted with water and extracted with chloroform (4 times). The organic layer was washed with saturated sodium bicarbonate and water and then 1N HCl and water, dried over anhydrous sodium sulfate, filtered, and concentrated to afford piperazine-1,2, 4- tricarboxylic acid 4-tert-butyl ester 1- (9H-fluoren-9-ylmethyl) ester (4.3g)., 128019-59-0
The synthetic route of 128019-59-0 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; ASTRAZENECA AB; NPS PHARMACEUTICALS, INC.; WO2005/80386; (2005); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics