31166-44-6, 1-Cbz-Piperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Piperazine-1-carboxylic acid benzyl ester (8.00 g; 36.3 mmol), 2-fluoro-4-methyl-l-nitro;benzene (4.70 g; 30.3 mmol) and potassium carbonate (8.5 g; 61.5 mmol) were stirred 3 hours in 50 mL DMSO at 80¡ãC. The reaction mixture was cooled to room temperature and 250 mL water was added. The mixture was extracted with diethyl ether (2 x 250 mL). The organic phase was washed with water (100 mL), 1 N HC1 (2 x 100 mL), brine (2 x 100 mL), dried with MgSC>4 and concentrated in vacuo to give 10.5 g (29.5 mmol; 97.6 percent) 4-(5-methyl-2-nitro-phenyl)-piperazine-l-carboxylic acid benzyl ester.
31166-44-6, As the paragraph descriping shows that 31166-44-6 is playing an increasingly important role.
Reference£º
Patent; H. LUNDBECK A/S; WO2006/7843; (2006); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics