With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.182618-86-6,1-Boc-4-(4-Nitrophenyl)piperazine,as a common compound, the synthetic route is as follows.
General procedure: b (8 g, 26.03 mmol) was added in sequence to 50 mL of ethanol.Palladium carbon (1.38g, content 10%), stirring under normal temperature for 5h under hydrogen atmosphere, after the reaction is completed, the palladium carbon is removed by filtration, and the filtrate is evaporated to dryness to obtain c (6.2g);The yield was 85.88%., 182618-86-6
182618-86-6 1-Boc-4-(4-Nitrophenyl)piperazine 3380696, apiperazines compound, is more and more widely used in various fields.
Reference£º
Patent; Zhejiang University; Zhengzhou University; Sun Yi; Liu Hongmin; Xu Tiantian; Li Yanan; Yu Bin; Ma Qisheng; Hou Tingjun; Pan Peichen; Xiong Xiufang; (37 pag.)CN110156729; (2019); A;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics