With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.115619-01-7,4-(4-Ethylpiperazin-1-yl)phenylamine,as a common compound, the synthetic route is as follows.
2,3-dichloro-1,4-naphthoquinone (0.37 g, 1.60 mmol) andA mixture of 4-(4-methylhexahydropyrazin-1-yl)aniline (0.3 g, 1.46 mmol) was dissolved in EtOH (5 ml).The reaction was stirred and allowed to reflux for 16 h. The residue was purified by flash column on silica gel (dichloromethane: methanol = 29: 1) to give 77 (0.10 g, 17.30%)., 115619-01-7
As the paragraph descriping shows that 115619-01-7 is playing an increasingly important role.
Reference£º
Patent; TAIPEI MEDICAL UNIVERSITY (TW); YEN, YUN (US); LIOU, JING PING (TW); PAN, SHIOW LIN (TW); (56 pag.)TW2018/5267; (2018); A;,
Piperazine – Wikipedia
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