630125-91-6, 4-((4-Ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
630125-91-6, A mixture of 4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline (7, 17.5 mg, 0.06 mmol), triethylamine (0.014 mL, 0.1 mmol), and p-nitrophenyl chloroformate (12.4 mg, 0.06 mmol) in 1,4-dioxane (5 mL) was heated at 60 C for 2 h. A solution of 6a (20 mg, 0.06 mmol) in 1,4-dioxane (5 mL) was slowly added thereto. The reaction mixture was heated at 90 C overnight. The reaction mixture was concentrated under reduced pressure and then partitioned between water (5 mL) and ethyl acetate (5 mL). The organic layer was separated and the aqueous layer was then extracted with ethyl acetate (3 ¡Á 3 mL). The combined organic extracts were washed with brine and dried over anhydrous Na2SO4. After evaporation of the organic solvent, the residue was purified by column chromatography (silica gel, hexane-ethyl acetate 3:1 v/v then switching to hexane-ethyl acetate 1:1 v/v) to yield compound 8g (6.0 mg, 15%).
As the paragraph descriping shows that 630125-91-6 is playing an increasingly important role.
Reference£º
Article; El-Gamal, Mohammed I.; Jung, Myung-Ho; Lee, Woong San; Sim, Taebo; Yoo, Kyung Ho; Oh, Chang-Hyun; European Journal of Medicinal Chemistry; vol. 46; 8; (2011); p. 3218 – 3226;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics