314741-40-7, (S)-tert-Butyl 3-(hydroxymethyl)piperazine-1-carboxylate is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
A solution of (3 ?)-3-methyl-6-(2- methyloxiran-2-yl)-3,4-dihydro-lH-isochromen-l-one (598 mg, 2.74 mmol) and tert-butyl (35)- 3 -(hydroxymethyl)piperazine-l -carboxylate (770 mg, 3.56 mmol dissolved in EtOH (15mL) was heated in a sealed tube to 110C for 14 hours. The reaction was cooled and concentrated to give crude product which was purified via MPLC (30-80%) EtOAc/Hexane) to give the title compound as a mixture of diastereomers: LC-MS: (M+l)+ 435;, 314741-40-7
The synthetic route of 314741-40-7 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; MERCK SHARP & DOHME CORP.; PIO, Barbara; PASTERNAK, Alexander; SHAHRIPOUR, Aurash; TANG, Haifeng; WALSH, Shawn; WO2013/90271; (2013); A1;,
Piperazine – Wikipedia
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