115619-01-7, 4-(4-Ethylpiperazin-1-yl)phenylamine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: The reaction vessel was charged with 5-((3-fluorophenyl)sulfonyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole-3-carboxylic acid(29 mg, 0.16 mmol), diisopropylethylamine (0.035 mL, 0.2 mmol), 1-hydroxybenzotriazole monohydrate (19 mg, 0.12 mmol) and dichloromethane (2 mL) were added and stirred. 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (EDCI ?? HCl, 23 mg, 0.12 mmol) was added thereto and stirred at room temperature. The reaction mixture was diluted with dichloromethane (10 mL), water (10 mL) was added, and the mixture was stirred. The organic layer was washed with brine, dried over anhydrous magnesium sulfate and concentrated. The residue was purified by column chromatography (silica gel, dichloromethane: methanol = 30: 1) to obtain the desired compound (50 mg, 90% yield).
115619-01-7, As the paragraph descriping shows that 115619-01-7 is playing an increasingly important role.
Reference£º
Patent; Korea Institute of Science and Technology; Sim Tae-bo; Noh Eun-ju; Yang Han-yong; (33 pag.)KR101936851; (2019); B1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics