70261-82-4, 4-(4-Methylpiperazin-1-ylmethyl)phenylamine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,70261-82-4
[00456] The title compound was prepared according to synthesis procedure B described above from 2-chloro-4-(3-chloro-4-fluorophenyl)-5-methylpyrimidine and 4-((4- methylpiperazin-l-yl)methyl)aniline in 84% yield (yellow solid) after purification by flash chromatography (CH2C12/CH30H 99: 1 gradually increasing to 95:5). 1H NMR (400 MHz, CDC13): delta 8.30 (s, 1H), 7.70 (m, 1H), 7.56 (d, 2H, J = 8.6 Hz), 7.51 (m, 1H), 7.25 (d, 2H, J: not calculated due to overlapping peaks), 7.05 (s, 1H), 3.46 (s, 2H), 2.46 (bs, 8H), 2.28 (s, 3H), 2.25 (s, 3H); MS (ESI): 426.3 [M+H]+, 213.7 [M+2H]2+.
The synthetic route of 70261-82-4 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; UNIVERSITY OF UTAH RESEARCH FOUNDATION; BEARSS, David, J.; VANKAYALAPATI, Hariprasad; MOLLARD, Alexis; WARNER, Steven, L.; SHARMA, Sunil; WO2012/135800; (2012); A1;,
Piperazine – Wikipedia
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