13889-98-0, 1-Acetylpiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,13889-98-0
To a 500 mL round bottom flask with a mechanical stirrer, temperature probe and under a nitrogen atmosphere was added N-acetylpiperazine (10 g, 80 mmol), DMF (150 mL), K2CO3 (16.6 g, 120 mmol) and 4-fluorobenzaldehyde (9.9 g, 80 mmol). The reaction mixture was heated to 100 C. for 20 hours. Followed the reaction by TLC monitoring the aldehyde consumption (Conditions: 20% EtOAc/hexane). After the reaction was complete water (150 mL) was added and cooled to room temperature. Extracted with MTBE (200 mL) and then EtOAc (200 mL). Concentrated the organic layer on the rotovap to yield the product.
As the paragraph descriping shows that 13889-98-0 is playing an increasingly important role.
Reference£º
Patent; Milliken & Company; Valenti, Dominick J.; Dey, Sanjeev K.; Qin, Haihu; Freund, Wesley A.; Miracle, Gregory S.; (24 pag.)US2019/112488; (2019); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics