One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time. 300543-56-0, Name is (R)-1-((4-Chlorophenyl)(phenyl)methyl)piperazine, formurla is C17H19ClN2. In a document, author is Bari, Darakhshan Gazala, introducing its new discovery. Product Details of 300543-56-0.
SYNTHESIS, CHARACTERIZATION AND PHARMACOLOGICAL EVALUATION OF SOME ARYL PIPERAZINE COMPOUNDS
In this planed research work, aryl piperazine derivatives will be synthesized because aryl piperazine currently the most important constructive block in drug discovery with positive pharmacological evaluation. A series N- (4-(benzo[d]thiazol-2-yl) phenyl)-2-[4-(arylsubstituted) piperazines-1-yllacetamide, N-(4-(benzo[d]oxazol-2-yl)phenyl)2-[4-(arylsubstituted)piperazines-1-yl]acetamide and Synthesis of N-(4(benzo[d]imidazol-2-yl) phenyl)- 2- (4-(arylsubstituted)piperazin-1-yl) acetamide will be synthesized with their characterization such as melting point determination, Thin-layer chromatography (TLC) and spectral analysis. After that, pharmacological evaluation, such as antibacterial activity, will be performed for synthesized compounds. All the synthesized compounds were reported for determination of zone of inhibition (mm), minimum inhibitory concentrations (MIC) were also calculated for effective derivatives, with an objective to offer some potent antimicrobial agents to human beings. Antimicrobial activity is determined based on their in-vitro activity in pure cultures. In-vitro susceptibility testing is done by two methods i.e.. Turbidimetric/photometric/tube dilution method and agar diffusion/cupplat/cylinder plate method.
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Reference:
Piperazine – Wikipedia,
,Piperazines – an overview | ScienceDirect Topics