21655-48-1, cis-2,6-Dimethylpiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a stirred suspension of 1?fluoro?4?nitrobenzene (562 mg, 3.98 mmol) and potassium carbonate (688 mg, 4.98 mmol) in anhydrous DMSO (2 mL) was added (2S,6R)?2,6? dimethylpiperazine (500 mg, 4.38 mmol) and the mixture heated at 100 ¡ãC for 16 h. After cooling the mixture wassuspended in water (40 mL) and filtered under vacuum to afford the title compound (889 mg, 95percent) . ?H NMR (500 MHz, DMSO?d6) : 3 8.03 (d, 2H) , 7.03 (d, 2H) , 3.88 (dd, 2H) 2.75?2.79 (m, 2H), 2.37?2.42 (m, 2H), 2.28 (br s, 1H),1.03 (d, 6H) . LCMS (Method C) : = 0.51 mi m/z = 236[M+H]., 21655-48-1
As the paragraph descriping shows that 21655-48-1 is playing an increasingly important role.
Reference£º
Patent; ALMAC DISCOVERY LIMITED; HARRISON, Timothy; TREVITT, Graham; HEWITT, Peter Robin; O’DOWD, Colin Roderick; BURKAMP, Frank; WILKINSON, Andrew John; SHEPHERD, Steven D.; MIEL, Hugues; WO2015/92431; (2015); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics