Simple exploration of 1-Boc-3-Oxopiperazine

The synthetic route of 76003-29-7 has been constantly updated, and we look forward to future research findings.

76003-29-7,76003-29-7, 1-Boc-3-Oxopiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Will be 49.94mmol3-oxo-1-piperazinecarboxylic acid tert-butyl ester1 dissolved in 100 mL of tetrahydrofuran,Add 51.4 mmol of 60% NaH to the temperature below zero, stir for 30 minutes, then add 25.5 mL of ethyl bromide and reflux for 3 hours.It was quenched by cooling with water, extracted with ethyl acetate and dried.Spin dry to obtain 10.8 g of compound 2, the recovery of compound 2 was 95%;

The synthetic route of 76003-29-7 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Shanghai Changtai Biological Technology Co., Ltd.; Lu Qian; Kuang Yi; Li Guohua; (9 pag.)CN108822048; (2018); A;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics