30459-17-7, 1-(4-Trifluoromethylphenyl)piperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: To the stirred solution of 4-oxo-3, 4-dihydroquinazoline-2-carboxylic acid (0.1 g, 0.0005 mol) in N,N-dimethyl formamideDMF, N-phenyl piperzine derivatives (0.0005 mol),or 3-(4-phenylpiperazin-1-yl)propan-1-amine derivatives(9a-g, 0.0005 mol) were added at room temperature, followedby the addition of EDC HCl (0.0006 mol) and HOBt(0.0006 mol) and the mixture was stirred for 1 h. Aftercompletion of the reaction (TLC analysis), small amount ofice cold water (10 mL) was added to the reaction mixtureand then extracted with chloroform (2 ¡Á 10 mL). Thechloroform layer was separated, dried over Na2SO4, andevaporated under vacuum to give corresponding hybrids(10a-g, 11a-g) in good yields., 30459-17-7
The synthetic route of 30459-17-7 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Venkatesh, Ramineni; Kasaboina, Suresh; Janardhan, Sridhara; Jain, Nishant; Bantu, Rajashaker; Nagarapu, Lingaiah; Medicinal Chemistry Research; vol. 25; 9; (2016); p. 2070 – 2081;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics