142-64-3, Piperazine Dihydrochloride is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Compound, 2 (250 mg, 1.23 mmol) was taken in THF, and piperazinedihydrochloride (199 mg, 1.25 mmol) and K2CO3 (690mg, 5 mmol) were added. The reaction mixture was refluxed overnight.After complete reaction the solvent was removed under reduced pressure and theprecipitate obtained was washed with water and hexane (5 x 3ml). The crudeproduct was purified by column chromatographyusing gradient of ethylacetate andhexane (20 % v/v) to obtain off white color compound. Yield 80 % (250mg). M.p. 91-92C. 1H NMR(300 MHz, CDCl3) delta (ppm): 7.38-7.12 (m, 10 H), 4.21 (s, 1H),2.40 (Br, 8 H).
142-64-3, As the paragraph descriping shows that 142-64-3 is playing an increasingly important role.
Reference£º
Article; Srivastava, Priyanka; Ali, Rashid; Razi, Syed S.; Shahid, Mohammad; Patnaik, Satyakam; Misra, Arvind; Tetrahedron Letters; vol. 54; 28; (2013); p. 3688 – 3693;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics