109-07-9, 2-Methylpiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
A solution of 4-chlorophenyl isothiocyanate (8.0 g, 47.17 mmol) in dichloromethane (250 mL) was added dropwise over 30 minutes to an ice cooled solution of 2-methylpiperazine (9.45 g, 94.33 mmol) in dichloromethane (250 mL). Once the addition was complete, the reaction was stirred at room temperature for an hour. The reaction was then washed with water (3¡Á), dried over MgSO4 and concentrated under reduced pressure, to give the title compound as a white solid, 11.8 g. 1H NMR (400 MHz, CDCl3): delta 1.08 (d, 3H), 2.70 (m, 1H), 2.88 (m, 2H), 3.02 (m, 2H), 4.43 (m, 2H), 7.10 (m, 2H), 7.29 (m, 2H). LCMS: m/z ES+270.1 [MH]+
109-07-9, The synthetic route of 109-07-9 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Pfizer Inc; US2005/154024; (2005); A1;,
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