20327-23-5, 1-Cyclopropylpiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: A mixture of aryl bromide (concentration 0.1-1 M), alkyl amine (2 eq, 0.2-2 M), Pd2(dba)3 (0.1-0.15 eq), X-Phos or BINAP (0.2-0.3 eq), t-BuONa (4-6 eq) or Cs2CO3 (2-4 eq) in toluene was stirred at 75-120 C overnight. After completion, the reaction mixture was concentrated under vacuum and purified by column chromatography to afford the desired product.d, 20327-23-5
The synthetic route of 20327-23-5 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; X4 PHARMACEUTICALS, INC.; BOURQUE, Elyse Marie Josee; SKERLJ, Renato; (279 pag.)WO2017/223229; (2017); A1;,
Piperazine – Wikipedia
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