13484-40-7, 1-(2-Methoxyethyl)piperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
13484-40-7, General Method FFl F2 F3Fl (1 equiv) was dissolved in CH2Cl2 (2 mL) and F2 (1.0-1.1 equiv) was added. The reaction mixture was stirred at room temperature for 3 hours whereafter it was washed with saturated NaHCO3 (2 mL). The organic phase was dried (Na2SO4), filtered and concentrated to afford F3.Example 44(a) l~[(4-Bromophenyl)sulfonyl]-4-(2-methoxyethyl)piperazineThe title compound was prepared in accordance with the general method F using 4- bromobenzenesulfonyl chloride (201.7 mg, 0.789 mmol) and l-(2- methoxyethyl)piperazine (113.8 mg, 0.789 mmol) to give the title compound (277 mg,97%).1H NMR (400 MHz, CDCl3) delta ppm 7.64 – 7.69 (m, 2 H) 7.57 – 7.62 (m, 2 H) 3.47 (t, J=5.2 Hz, 2 H) 3.30 (s, 3 H) 3.08 (s, 4 H) 2.62 (d, J=4.8 Hz, 6 H); MS (ESI) m/z 364 (M + 1).
The synthetic route of 13484-40-7 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; ASTRAZENECA AB; WO2007/40440; (2007); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics