4318-42-7 1-Isopropylpiperazine 78013, apiperazines compound, is more and more widely used in various fields.
4318-42-7, 1-Isopropylpiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Step 1 l-Isopropyl-4-(5-niotatro-pyriotadiotan-2-yl)-piotaperaziotane [00408] To a solution of 2-chloro-5-mtropyridme (2 5g, 15 7mmol) m THF (25mL), are added1-isopropylpiperazme (2 Olg, 15 7mmol) and K2CO3 (3 25g, 23 6mmol) The reaction mixture is stirred at 500C for 4 hours and then at 7O0C overnight The solvent is removed in vacuo and the resultant orange solid is triturated using 10 1 petroleum ether-diethyl ether The isolated compound (3 7g, 94percent) is used m the next step without further purification, 4318-42-7
4318-42-7 1-Isopropylpiperazine 78013, apiperazines compound, is more and more widely used in various fields.
Reference£º
Patent; GALAPAGOS N.V.; WO2007/131991; (2007); A1;,
Piperazine – Wikipedia
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