171504-98-6, Methyl 1,4-Bis(Boc)-2-piperazinecarboxylate is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Add 1,4-di-tert-butyl 2-methylpiperazine-1,2,4-tricarboxylate (10 g) to the dry reaction flask.29.04mmol),Anhydrous tetrahydrofuran (100 mL),Under nitrogen protection, cool down to -78 C,Slowly add LiHDMS (35 mL, 35 mmol, 1 mol/L).After stirring for 2 h, iodomethane (3.7 mL, 59 mmol) was added.Stirring was continued for 1 h, slowly warmed to room temperature, and stirring was continued for 12 h.The reaction was quenched by adding a saturated aqueous solution of ammonium chloride (50 mL), and then ethyl acetate(100 mL ¡Á 2), the organic layer was combined, and the organic layer was evaporated. ),The title compound was obtained as a colorless oil (8.2 g, 79%)
171504-98-6, As the paragraph descriping shows that 171504-98-6 is playing an increasingly important role.
Reference£º
Patent; Guangdong Dongyangguang Pharmaceutical Co., Ltd.; Liu Xinchang; Ren Qingyun; Yan Guanghua; S ¡¤geerdeman; Zhang Yingjun; (200 pag.)CN109678859; (2019); A;,
Piperazine – Wikipedia
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