With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.78551-60-7,tert-Butyl 4-benzyl-3-oxopiperazine-1-carboxylate,as a common compound, the synthetic route is as follows.
EXAMPLE 42 4-t-butoxycarbonyl-3-[2-(methylthio)ethyl)-1-(phenylmethyl)piperazinone (XVI) Following the general procedure of Example 47 and making non-critical variations, but substituting 4-t-butoxycarbonyl-1-(phenylmethyl)piperazinone (XV, Example 41) for 1-methyl-4-(phenylmethyl)piperazinone and 1-chloro-2-(methylthio)ethane [Chem. Ber., 84, 911 (1951)] for 1-bromo-2-methylpropane, there is obtained the title compound., 78551-60-7
As the paragraph descriping shows that 78551-60-7 is playing an increasingly important role.
Reference£º
Patent; The Upjohn Company; US4251438; (1981); A;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics